What Is 4-Propylphenylboronic Acid CAS 134150-01-9? Properties, Uses, and Supplier Information

4-Propylphenylboronic acid, identified by CAS 134150-01-9, is an aryl boronic acid used mainly as a synthetic building block in organic and medicinal chemistry. Its molecular formula is C₉H₁₃BO₂, and its calculated molecular weight is approximately 164.01 g/mol. The molecule contains a boronic acid group attached to the para position of a propyl-substituted phenyl ring, making it suitable for carbon–carbon bond-forming reactions such as Suzuki–Miyaura coupling.

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At Maison Chemical, I position this product for research, process development, and commercial sourcing teams that need a defined aryl boronic acid intermediate. The appropriate grade, package size, analytical documentation, and shipping arrangement depend on the intended application. Buyers should confirm identity, assay, impurity limits, moisture sensitivity, and delivery requirements before placing a purchase order.

Key Takeaways

• 4-Propylphenylboronic acid is an aromatic boronic acid and an organic synthesis intermediate.
• Its CAS number is 134150-01-9, its formula is C₉H₁₃BO₂, and its approximate molecular weight is 164.01 g/mol.
• Its principal technical value is participation in cross-coupling chemistry, especially Suzuki-type reactions.
• It can support pharmaceutical, agrochemical, materials, and academic research workflows when the required reaction and quality profile are appropriate.
• Maison Chemical can discuss product documentation, packaging, export coordination, and project-specific supply requirements.

What Is 4-Propylphenylboronic Acid?

4-Propylphenylboronic acid is an organoboron compound in which a boronic acid group, –B(OH)₂, is connected to an aromatic ring carrying a propyl substituent at the para position. This structure gives the molecule two important characteristics: an aryl group that can be transferred during coupling chemistry and a boronic acid function that can participate in controlled synthetic transformations. In practical terms, it is used as a building block rather than as a finished active ingredient.

The compound is also described as 4-propylbenzeneboronic acid or 4-propylphenylboronic acid. The CAS identifier 134150-01-9 helps purchasing and laboratory teams distinguish this material from positional isomers, protected boronate esters, and other alkyl-substituted phenylboronic acids. Because naming conventions can vary between catalogs and internal systems, I recommend confirming the CAS number together with the molecular structure before technical approval.

Basic Chemical Identity

Core Functions and Chemical Value

The main function of 4-propylphenylboronic acid is to act as a coupling partner in the construction of biaryl, heteroaryl–aryl, and related carbon–carbon frameworks. In a typical Suzuki–Miyaura reaction, the aryl boronic acid reacts with an aryl or heteroaryl halide in the presence of a suitable palladium catalyst, base, solvent, and reaction system. The final product incorporates the propylphenyl fragment into a larger molecule.

The boronic acid group is valuable because it is generally compatible with a broad range of synthetic planning strategies. It can be selected when a chemist wants to introduce a para-propyl-substituted aromatic unit at a defined stage of a route. Reaction performance still depends on the coupling partner, catalyst, base, solvent, temperature, concentration, and work-up procedure, so I do not treat the material as a universal solution for every cross-coupling process.

Where It Fits in Synthetic Planning

I typically view this compound as a route-enabling intermediate for medicinal chemistry libraries, process research, and the preparation of advanced aromatic building blocks. The propyl group can modify the steric and lipophilic characteristics of a target molecule, while the boronic acid group provides a practical point for further functionalization. Whether those properties are beneficial must be evaluated against the target structure and the required biological, material, or process performance.

Application Scenarios

Pharmaceutical and Medicinal Chemistry

Medicinal chemists may use 4-propylphenylboronic acid to prepare analogs containing a para-propylphenyl moiety. It can support small-molecule diversification when the research objective is to compare aromatic substituents across a compound series. The material is a research intermediate and should not be described as a pharmaceutical ingredient unless it has separately been qualified for that specific use.

Agrochemical and Specialty Chemical Research

In agrochemical and specialty chemical development, aryl boronic acids can contribute to the synthesis of screening compounds and advanced intermediates. The value of this specific compound depends on whether the propylphenyl fragment is present in the desired structure and whether the route provides acceptable conversion and purification. Project teams should assess downstream specifications rather than selecting the material only by name.

Materials and Academic Research

Researchers working on functional aromatic molecules, ligands, and conjugated structures may also evaluate this building block. Its use can be relevant when a para-substituted aryl unit is required for molecular design or library preparation. In academic and early-stage work, small quantities may be suitable, while process development normally requires additional attention to lot consistency, impurity control, and scale-up documentation.

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Types and Material Options to Consider

When I discuss sourcing with a buyer, I separate the chemical identity from the commercial presentation. The same CAS number may be requested in a small research package, a larger development package, or a project-specific quantity, but each option can require different documentation and handling arrangements. Buyers should also distinguish the free boronic acid from related products such as pinacol boronate esters, because they are not interchangeable in every procedure.

• Research quantity: suitable for route scouting, method development, and small-scale screening.
• Development quantity: intended for repeated experiments, process evaluation, and more extensive analytical review.
• Project-specific supply: evaluated according to required quantity, packaging, specification, and delivery destination.
• Related boronate forms: chemically related alternatives may be considered, but their reactivity, stability, and work-up behavior must be reviewed separately.

Key Specifications Buyers Should Review

A purchasing specification should normally include product name, CAS number, molecular formula, molecular weight, assay or purity requirement, appearance description, and packaging. Depending on the application, buyers may also request water content, residual solvents, elemental impurities, chromatographic impurity data, and a defined retest or storage statement. I recommend using the current product specification and certificate of analysis rather than relying only on a marketplace description.

Analytical confirmation may include chromatographic testing, spectroscopic identification, and other methods selected by the supplier or customer quality system. The exact test method, acceptance limit, and reporting format should be agreed before order confirmation. If the material will enter a regulated development route, the buyer should communicate documentation expectations at the inquiry stage.

How to Select a Supplier

Identity and Quality Documentation

I advise buyers to begin with traceable identity information and a lot-specific certificate of analysis. The document should correspond to the shipped batch and should clearly identify the CAS number, test results, units, and specification limits. If a supplier cannot explain how batch identity and release testing are managed, the sourcing risk is higher.

Quantity, Packaging, and Logistics

Quantity is not the only commercial consideration. Packaging should be appropriate for the product, shipment route, and customer handling procedure, while export documentation should match the destination and declared material information. Maison Chemical can discuss available package options, quantity requirements, shipping destinations, and the documentation needed for a practical quotation.

Technical Communication

A responsive supplier should be able to answer basic questions about product identity, available quality level, lead-time expectations, and inquiry handling. I also recommend providing the intended application, target quantity, destination country, and required delivery date in the first request. This information helps Maison Chemical assess the appropriate supply route instead of issuing a generic offer that may not fit the project.

Supplier Support from Maison Chemical

Maison Chemical supplies 4-Propylphenylboronic acid CAS 134150-01-9 for customers in chemicals, organic synthesis, and related research applications. I support the inquiry process by helping buyers align the requested identity, quantity, specification, packaging, and shipping information. The final commercial offer should be based on the actual order requirements and the documentation available for the relevant batch.

For development or repeat purchasing, I can also discuss a more structured supply plan, including expected quantity ranges, quality documentation, and delivery coordination. I do not recommend assuming that a small laboratory package and a larger process quantity have identical commercial conditions. Confirming these details early can reduce delays during qualification and purchasing approval.

Conclusion: Is 4-Propylphenylboronic Acid Right for Your Project?

4-Propylphenylboronic acid CAS 134150-01-9 is an aryl boronic acid building block with the formula C₉H₁₃BO₂ and an approximate molecular weight of 164.01 g/mol. Its primary use is to introduce a para-propylphenyl fragment through cross-coupling and related organic synthesis routes. It is therefore most suitable when your target structure specifically requires this substitution pattern and your reaction development confirms acceptable performance.

The next step is to prepare a clear inquiry stating the required quantity, purity or assay target, packaging preference, destination, and documentation requirements. Maison Chemical can then review the sourcing details and provide a product-specific quotation and supply discussion. Contact Maison Chemical with your project parameters to evaluate the most suitable purchasing and delivery option for 4-Propylphenylboronic acid.

Contact us to discuss your requirements of 4-Propylphenylboronic acid CAS 134150-01-9. Our experienced sales team can help you identify the options that best suit your needs.